School of Veterinary Medicine, Department of Veterinary Science
北澤多喜雄 キタザワ タキオ
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Last Update :2020/08/06

Researcher Profile and Settings

Name

KITAZAWA Takio

Affiliation (Master)

School of Veterinary Medicine, Department of Veterinary Science

Education

  1979 04  - 1981 03 , Hokakido University Graduate School
  1975 04  - 1979 03 , Hokkaido University, Veterinary Medicine

Degree

獣医学博士, 北海道大学

Association Memberships

The Japanese Society of Veterinary Nursing
JAPAN SOCIETY OF SMOOTH MUSCLE RESEARCH
THE JAPANESE PHARMACOLOGICAL SOCIETY
THE JAPANESE SOCIETY OF VETERINARY SCIENCE

Academic & Professional Experience

  1992 07  - Today, School of Veterinary Medicine, Rakuno Gakuen University
  2002 10  - 2003 10 , Visiting Professor, Gut Hormone Lab(TL Peeters), Leuven University (Belgium)
  1990 04  - 1992 06 , Kyowa Hakko Co.Ltd
  1991 05  - 1991 08 , School of Medicine, Nagasaki University
  1981 04  - 1990 03 , Kitasato University

Research Activities

Research Areas

Life sciences, Morphology, anatomy
Life sciences, Veterinary medicine, Comparative Animal Pharmacology
Life sciences, Veterinary medicine, Comparative Animal Pharmacology
Life sciences, Veterinary medicine, Comparative Animal Pharmacology

Research Interests

musucarinic receptor,
motilin, ghrelin,
Comparative Biology,
Gut hormone,
Autonomic nerve,
Gastrointestinal motility,
Pharmacology,

Published Papers

Identification of pheasant ghrelin and motilin and their actions on contractility of the isolated gastrointestinal tract.Identification of pheasant ghrelin and motilin and their actions on contractility of the isolated gastrointestinal tract., Gen Comp Endocrinol., Gen Comp Endocrinol., 285, 1, 12, 19, 20200100, Refereed
Genetic diversity of cytochrome P450 1A2 with different metabolic activities in domestic cats., Sugiyama S, Uno Y, Amano T, Kitazawa T, Teraoka H, J. Vte.Med. Sci, J. Vte.Med. Sci, 81, 7, 980, 982, 20190700, Refereed
Regulation of Gastrointestinal Motility by Motilin and Ghrelin in Vertebrates, Kitazawa Takio, Kaiya Hiroyuki, Frontier in Endocrinology, Frontier in Endocrinology, doi: 10.3389/fendo.2019.00278, 1, 19, 20190500, Refereed
Genetic diversity of cytochrome P450 3A with different metabolic activity in domestic cats., Sugiyama S, Uno Y, Amano T, Kitazawa T, Teraoka H, J. Veterinary Medical Science, J. Veterinary Medical Science, 81, 4, 598, 600, 20190400, Refereed
A verification study of gastrointestinal motility-stimulating action of guinea-pig motilin using isolated gastrointestinal strips from rabbits and guinea-pigs, Takio Kitazawa, Rio Harada, Ichiro Sakata, Takafumi Sakai, Hiroyuki Kaiya, General and Compaartive Endocrinology, General and Compaartive Endocrinology, 100, 1, 19, 28, 20190400, Refereed
Transcription profiling of cytocrome P450 genes in the liver of adult zebrafish, Danio rerio., Kubota A, Kawai Y, Yamashita N, Lee JS, Kondoh D, Zhang S, Nishi Y, Suzuki K, Kitazawa T, Teraoka H, The Journal of Toxicological Sciences, The Journal of Toxicological Sciences, 44, 5, 347, 356, 20190300, Refereed
Alpha1B-adrenoceptor-mediated positive inotropic and positive chronotropic actions in the mouse atrium, Shuangyi Zhang Reia Takahashi, Natsumi Yamashita, Hiroki Teraoka, Takio Kitazawa, European J Pharmacology, European J Pharmacology, 839, 1, 82, 88, 20181100, Refereed
Limited expression of functional cytochrome p450 2c subtypes in the liver and small intestine of domestic cats., Ono Y, Sugiyama S, Matsushita M, Kitazawa T, Amano T, Uno Y, Ikushiro S, Teraoka H, Xenobiotica., Xenobiotica., doi: 10.1080/00498254.2018.148, 1, 9, 20180600, Refereed
Contamination Status of Seven Elements in Hooded Cranes Wintering in South-West Kyushu, Japan: Comparison with Red-Crowned Cranes in Hokkaido, Japan., Teraoka H, Miyagi H, Haraguchi Y, Takase K, Kitazawa T, Noda J, Arch Environ Contam Toxicol., Arch Environ Contam Toxicol., doi: 10.1007/s00244-018-0541-y, 1, 8, 20180500, Refereed
Post-operative rehabilitation of a dog with tetraparesis resulting from cervical intervertebral disc herniation., Kitazawa Takio, Veterinary Nursing, Veterinary Nursing, 22, 2, 35, 40, 20180300, Refereed
Aroclor 1254 and BDE-47 inhibit dopaminergic function manifesting as changes in locomotion behaviors in zebrafish embryos, Tanaka Y, Fujiwara M, Shindo A, Yin G, Kitazawa T, Teraoka H, Chemosphere, Chemosphere, 193, 1207, 1215, 20180100, Refereed
Structural determination, distribution, and physiological actions of ghrelin in the gunea-pig, Okuhara Y, Kaiya H, Teraoka H, Kitazawa T, Peptides, Peptides, 99, 70, 81, 20180100, Refereed
Neuropeptide Y (NPY) inhibits spontaneous contraction of the mouse atrium by possible activation of the NPY1 receptor, Oki Y, Teraoka H, Kitazawa T, 37, 23, 28, 20170600, Refereed
Pharmacological characterization of muscarinic receptor subtypes involved in carbachol-induced contraction of the chicken proventriculus, Kitazawa Takio, Nahoko Kondo, Tetsuro Taneike, SM. J. Gastroenterol., SM. J. Gastroenterol., 2, 1, 1003, 1012, 20161000, Refereed
Age-dependent reduction of ghrelin- and motilin-induced contractile activity in the chicken gastrointestinal tract., Kitazawa T, Yoshida A, Tamano T, Teraoka H, Kaiya H, Peptides, Peptides, 43, 88, 95, 20130500, Refereed
A ganglionic stimulant, 1,1-dimethyl-4-phenylpiperazinium, caused both cholinergic and adrenergic responses in the isolated mouse atrium., Ochi K, Teraoka H, Unno T, Komori S, Yamada M, Kitazawa T, European journal of pharmacology, European journal of pharmacology, 704, 1-3, 7, 14, 20130300, Refereed
Evidence for M2 and M3 muscarinic receptor involvement in cholinergic excitatory junction potentials through synergistic activation of cation channels in the longitudinal muscle of mouse ileum., Matsuyama H, Tanahashi Y, Kitazawa T, Yamada M, Komori S, Unno T, Journal of pharmacological sciences, Journal of pharmacological sciences, 121, 3, 227, 236, 20130000, Refereed
Origin of three Red-crowned Cranes Grus japonensis found in northeast Honshu and west Hokkaido, Japan, from 2008 to 2012., Miura Y, Shiraishi J, Shiomi A, Kitazawa T, Hiraga T, Matsumoto F, Teraoka H, Masatomi H, The Journal of veterinary medical science, The Journal of veterinary medical science, 75, 9, 1241, 1244, 20130000, Refereed
Intracerebroventricular administration of Growth Hormone Releasing Peptide-6 (GHRP-6) inhibits food intake, but not food retention of crop and stomach in neonatal chicks, Khan MSI, Dodo KI, Yahata K, Nishimoto S, Ueda H, Taneike T, Kitazawa T, Hosaka Y, Bungo T, Journal of Poultry Science, Journal of Poultry Science, 43, 1, 35, 40, 20060100, Refereed
The mechanisms of alpha(2)-adrenoceptor agonist-induced contraction in longitudinal muscle of the porcine uterus, T Kitazawa, Y Maezono, T Taneike, EUROPEAN JOURNAL OF PHARMACOLOGY, EUROPEAN JOURNAL OF PHARMACOLOGY, 390, 1-2, 185, 195, 20000200, Refereed

Books etc

Regulation of heart contractility by M2 and M3 muscarinic receptors: functional studies using muscarinic receptor knockout mouse., Kitazawa T, Teraoka H, Harada N, Ochi K, Nakamura T, Asakawa K, Kanegae S, Yaosaka N, Unno T, Komori S, Yamada M, Joint author, Chapter 13, Muscarinic receptor. From Structure to Animal Models. Neuromethods Vol. 107. DOI 10.1007/978-1-4939-2858-3_13@Springer Science+Business Media New York. 2015. 235-259,   2015 08

Conference Activities & Talks

Cytochrome P450s expression and chemical metabolic activity before liver formation in zebrafish eleutheroembryos,   2019 12 03
Does motilin regulate gastrointestinal motility of bullfrog? In vitro study uisng isolated GI strips., Kitazawa Takio, Shuangyi Zhang, Teraoka Hiroki, Okuhara Yuji, Kaiya Hiroyuki, NeuroGastro 2019 (Lisobon),   2019 09 05
Identification of ghrelin and motilin in the pheasant , and their mechanical actions in the isolated gastrointestinal tract., Shuangyi Zhang, Ichiro Sakata, Hiroyuki Kaiya, HirokiTeraoka, Yuji Okuhara, Takio Kitazawa, NeuroGastro 2019,   2019 09 05
Transcriptional profiling of cytochrome P450 genes in adult liver and in whole embryo fry of zebrafish in some developmental stages, Hiroki Teraoka, Natsumi Yamashita, Yusuke K. Kawai, Shuangyi Zhang, Takio Kitazawa, Akira Kubota, 15th International Congress of Toxicology,   2019 07 15
Alpha1B-adrenoceptor-mediated positive inotropic and positive chronotropic actions in the mouse atrium, Zhang S, Takahashi R, Yamashita N, Teraoka H, Kitazawa T, 92nd Annual Meeting of Japan Pharmacological Society,   2019 03 15
A review of the motilin system in guinea-pig: Re-examination of gastrointestinal motility-stimulating action of guinea-pig motilin candidate in vitro, Kitazawa Takio, Hiroyuki Kaiya, 3rd meeting of the federation of neurogastroenterology and motility,   2018 08 30
Guinea-pig ghrelin, its structure, distribution and function in gastrointestinal trac, Takio Kitazawa, Yuji Okuhara, Hiroyuki Kaiya, Hiroki Teraoka, World Clinical Pharmacology 2018 Kyoto,   2018 07 03
Effects of prostaglandin E2 and F2 α on expression of growth factors and pro-, Shuangyi Zhang, Kitazawa Takio, Jinshan Cao, World Clinical Pharmacology 2018 Kyoto,   2018 07 02
Chicken is a unique animal model for studying function of ghrelin in gastrointestinal motility, Kitazawa Takio, International Symposium on Ghrelin and Energy metabolism Homeostasis,   2017 04 22
Possible regulation of gastrointestinal motility of zebrafish by motilin: An invitro study using isolated muscle strips, Kitazawa Takio, RegPep2016,   2016 07 13
What is the general action of ghrelin invertebrates? Study focused on gastrointestinal motor stimulating action, Kitazawa Takio,   2016 03 24

Misc

動物看護学課程で提供される望ましい野生動物(医)学教育とは―酪農学園大学獣医学群における事例から―, 浅川満彦, 郡山尚紀, 佐野忠士, 北澤多喜雄, Veterinary Nursing, 22, (1) 43 - 43,   2017 07 01 , http://jglobal.jst.go.jp/public/201802281387658677
イヌ血液中アミノ酸量の変化に基づいた腫瘍診断法の確立, 猿渡 菜美香, 大野 さや, 北澤 多喜雄, 井上 博紀, 福本 真也, 打出 毅, 遠藤 能史, 廉澤 剛, 岩野 英知, Veterinary Nursing, 22, (1) 29 - 29,   2017 07
犬血漿中アミノ酸量のバランス変化による腫瘍診断法の確立, 岩野英知, 猿渡菜美香, 大野さや, 樋口豪紀, 北澤多喜雄, 福本真也, 打出毅, 遠藤能史, 廉澤剛, 横田博, 北海道獣医師会雑誌, 60, (8) 406 - 406,   2016 08 10 , http://jglobal.jst.go.jp/public/201602243043412162
タンチョウの水銀蓄積特性に関する検討, 寺岡宏樹, 岡本絵梨佳, 久道萌, 中山翔太, 池中良徳, 石塚真由美, 北澤多喜雄, 環境化学討論会要旨集(CD-ROM), 24th,   2015 06 17 , http://jglobal.jst.go.jp/public/201602256310237529
Basic biochemical study for growth hormone secretagogue-receptor (GHS-R) 1a and plasma ghrelin in dogs, KITAZAWA Takio, ISHIDA Shoji, IWA Masaru, YAMAGATA Tomoya, OCHI Kenta, UCHIDA Eiji, HIRAGA Takeo, KAIYA Hiroyuki, Journal of the College of Dairying. Natural science, 36, (2) 295 - 310,   2012 04 , http://ci.nii.ac.jp/naid/110008923158
北海道におけるタンチョウの水銀汚染の原因についての検討, 岡本絵梨佳, 久道萌, 水野直治, 古賀公也, 志村良治, 中山翔, 池中良徳, 石塚真由美, 北澤多喜雄, 井上雅子, 百瀬邦和, 正富宏之, 寺岡宏樹, 寺岡宏樹, 日本鳥学会大会講演要旨集, 2011,   2011 09 13 , http://jglobal.jst.go.jp/detail.php?from=API&JGLOBAL_ID=201102276089792792
北海道におけるタンチョウの水銀汚染の原因についての検討, 岡本絵梨佳, 久道萌, 水野直治, 古賀公也, 志村良治, 中山翔, 池中良徳, 石塚真由美, 北澤多喜雄, 井上雅子, 百瀬邦和, 正富宏之, 寺岡宏樹, 日本鳥学会大会講演要旨集, 2011,   2011 09 13 , http://jglobal.jst.go.jp/public/201102276089792792
脊椎動物共通プライマーを用いた大規模ディファレンシャル・ディスプレイ法によるダイオキシン応答遺伝子の探索, 鵜飼 典佳, 遠藤 大二, 池田 晴喜, 伊藤 知子, 伊東 志野, 金 恩英, 岩田 久人, 北澤 多喜雄, 平賀 武夫, 寺岡 宏樹, 日本獣医学会学術集会講演要旨集, 150回,   2010 09
エコトキシコゲノミクスへの応用を目的とした半網羅的ディファレンシャル・ディスプレイ法, 伊東 志野, 遠藤 大二, 池田 晴喜, 伊藤 知子, 鵜飼 典佳, 金 恩英, 岩田 久人, 北澤 多喜雄, 平賀 武夫, 寺岡 宏樹, The Journal of Toxicological Sciences, 35, (Suppl.) S181 - S181,   2010 05
モチリン・アンタゴニストの同時投与がGHSアゴニストの摂食抑制作用に及ぼす影響, カーン シャキル.イスラム, 百々功一, 上田博史, 種池哲朗, 北沢多喜雄, 保坂善真, 高梨契典, 豊後貴嗣, 日本家禽学会誌, 42,   2005 10 15 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902244179925085
GHS‐R AgonistおよびAntagonist投与がニワトリヒナの摂食量,消化管通過に及ぼす影響, 百々功一, 上田博史, 種池哲朗, 保坂善真, 北沢多喜雄, 豊後貴嗣, 日本家禽学会誌, 42,   2005 03 10 , https://jglobal.jst.go.jp/detail?JGLOBAL_ID=200902294118268275
ブタ子宮に存在する収縮性及び弛緩性EP受容体subtypeの解析, 曹 金山, 田島 剛, 沙衣布扎提, 北澤 多喜雄, 種池 哲朗, 日本獣医学会学術集会講演要旨集, 133回,   2002 03
ブタ子宮におけるprostanoid受容体発現の筋層差, 田島 剛, 北澤 多喜雄, ミクラム・サイブザティ, 種池 哲朗, 日本獣医学会学術集会講演要旨集, 132回,   2001 09
ブタ子宮筋に存在するプロスタノイド受容体サブタイプの薬理学的解析, 沙衣布扎堤, 米克熱木, 畠山 洋文, 田島 剛, 北澤 多喜雄, 種池 哲朗, Journal of Smooth Muscle Research Japanese Section, 5, (2) J69 - J80,   2001 08 , 10.1540/heikatsukinzashi1997.5.J69
ブタ子宮におけるプロスタノイド受容体分布の筋層差, 北澤 多喜雄, 沙衣布扎提, 木, 田島 剛, 種池 哲朗, Journal of Smooth Muscle Research Japanese Section, 5, (1) J47 - J47,   2001 04


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