School of Veterinary Medicine, Department of Veterinary Medicine
翁長武紀 オナガ タケノリ
E-Mail:onaga@rakuno.ac.jp
Website:

Last Update :2019/09/30

Researcher Profile and Settings

Name

ONAGA Takenori

Affiliation (Master)

School of Veterinary Medicine, Department of Veterinary Medicine

Affiliation & Job

School of Veterinary Medicine Department of Veterinary Medicine

Education

 - 1990 , Rakuno Gakuen University, Faculty of Dairy Science

Degree

Ph. D.(Veterinary Medicine), Hokkaido University

Association Memberships

Japanese Society of Veterinary Science
Japanese Society of Animal Science
European Society of Neurogastroenterology and Motility
Physiological Society of Japan

Committee Memberships

  2008 , Japanese Society of Veterinary Science, trustee
  2009 , Physiological Society of Japan

Research Activities

Research Areas

Zootechnical science/Veterinary medical science, Basic veterinary science/Basic zootechnical science

Research Interests

Gastrointestinal Motility,
Comparative Endocrinology,
Enteric Nervous System,
Parasympathetic Nerve,
PACAP,
PYY,
NO,
EGF,
Ruminants,
Rumen,
Abomasum,
Small Intestine,
Pancreas,

Published Papers

Role of neurotensin in the regulation of gastric motility in healthy conscious sheep, Onaga T, Shimoda T, Ohishi T, Yasui Y, Hayashi H, Small Ruminant Research, 172, 31, 41, 20190100, Refereed
Polymeric immunoglobulin receptor expression and local immunoglobulin A production in bovine sublingual, submandibular and parotid salivary glands, Sakaguchi, K. Yokota, H. Miyasho, T. Maeda, N. Nakamura, K. Onaga, T. Koiwa, M. Matsuda, K. Okamoto, M. Hirayama, K. Taniyama, H., Vet J, 197, 2, 291, 296, 20130000, Refereed
A case of preliminary utilization of commercial ELISA kit for detecting excretion of Urinary 8-hydroxyguanosine (8-OHdG) in captive chimpanzees, Pan troglodytes, Ohshima, Yuko, Ai Mizuo, Keiko Sugama, Genichi Idani, Ryoji Shimura, Akiko Uebayachi, Satoru Takahashi, Manabu Onuma, Takenori Onaga, Katsuro Hagiwara, Mutsuhiko Asakawa, Journal of Jpn. Assoc. Zoo Aqu., 52, 4, 140, 144, 20120000, Refereed
Preliminary research on the excretion of uninary 8-hydroxyguanosine (8-OHdG) as a marker of protozoan parasites infection in cative western lowland gorillas (Gorilla gorilla gorilla), Mizuo, A., Ohshima, Y., Imanishi, R., Kitada, Y., Kasahara, M., Hashizaki, F., Wada, S., Matsunaga, M., Takai, S., Onuma, M., Onaga, T., Hagiwara, K., Sanada, Y., Asakawa, M., Japanese Journal of Zoo and Wildlife Medicine, 14, 1, 77, 80, 20090000, Refereed
Effect of intravenous infusion of proglumide on ruminal motility in conscious sheep (Ovis aries), Takenori Onaga, Vet Res Commun, 31, 8, 1021, 1036, 20070000, Refereed
Multiple regulation of peptide YY secretion in the digestive tract, Onaga, T. Zabielski, R. Kato, S., Peptides, 23, 2, 279, 290, 20020000, Refereed
Role of peptide tyrosine tyrosine (PYY) in the regulation of gastrointestinal motility and pancreatic exocrine secretion in sheep, Takenori Onaga, Hokkaido University, 20010000
PGE2 inhibits glucose uptake in isolated villous epithelial cells of the ovine small intestine, Hyun, H. S. Arai, S. Onaga, T. Kato, S., Zentralbl Veterinarmed A, 44, 7, 443, 447, 19970000, Refereed
Effects of proglumide on cholecystokinin-8-induced exocrine and endocrine pancreatic responses in conscious sheep, Mineo, H. Iwaki, N. Kogishi, K. Onaga, T. Kato, S. Zabielski, R., Comp Biochem Physiol A Physiol, 118, 3, 759, 764, 19950000, Refereed
Intraduodenal cholecystokinin octapeptide (CCK-8) can stimulate pancreatic secretion in the calf, Zabielski, R. Onaga, T. Mineo, H. Kato, S. Pierzynowski, S. G., Int J Pancreatol, 17, 3, 271, 278, 19950000, Refereed
Effects of intravenous infusions of cholecystokinin-8 and pentagastrin on plasma concentrations of insulin and glucagon in sheep, Mineo, H. Iwaki, N. Onaga, T. Kato, S., Res Vet Sci, 56, 3, 298, 302, 19940000, Refereed
Effect of cholecystokinin octapeptide on contraction of bovine ruminal muscle, Onaga, T., S. Kato, H. Mineo, & J. Ushijima, Asian-Australasian Journal of Animal Science, 2, 165, 166, 19890000
Characterization of feline cytochrome P450 2B6., Okamatsu G, Komatsu T, Ono Y, Inoue H, Uchide T, Onaga T, Endoh D, Kitazawa T, Hiraga T, Uno Y, Teraoka H, Xenobiotica; the fate of foreign compounds in biological systems, 47, 2, 93, 102, 20170200, Refereed
Identification and functional characterization of novel feline cytochrome P450 2A., Okamatsu G, Komatsu T, Kubota A, Onaga T, Uchide T, Endo D, Kirisawa R, Yin G, Inoue H, Kitazawa T, Uno Y, Teraoka H, Xenobiotica; the fate of foreign compounds in biological systems, 45, 6, 503, 510, 20150000, Refereed
Assessment of testicular corticosterone biosynthesis in adult male rats., Maeda N, Tahata S, Yagi T, Tanaka E, Masu K, Sato M, Haeno S, Onaga T, Yokota H, PloS one, 10, 2, e0117795, 20150000, Refereed
Tachykinin: recent developments and novel roles in health and disease., Onaga T, Biomolecular concepts, 5, 3, 225, 243, 20140600, Refereed
Role of tachykinins and neurokinin receptor subtypes in the regulation of motility of the forestomach and abomasum in conscious sheep., Oh-ishi T, Shimoda T, Hayashi H, Onaga T, Neuropeptides, 47, 1, 9, 18, 20130200, Refereed
Fatty acid-binding protein expression in the gastrointestinal tract of calves and cows., Hayashi H, Maruyama S, Fukuoka M, Kozakai T, Nakajima K, Onaga T, Kato S, Animal science journal = Nihon chikusan Gakkaiho, 84, 1, 35, 41, 20130100, Refereed
Role of tachykinin and neurokinin receptors in the regulation of ovine omasal contractions., Onaga T, Oh-ishi T, Shimoda T, Nishimoto S, Hayashi H, Regulatory peptides, 173, 1-3, 64, 73, 20120100, Refereed
Ghrelin stimulates gastric motility of the guinea pig through activation of a capsaicin-sensitive neural pathway: in vivo and in vitro functional studies, Nakamura, T. Onaga, T. Kitazawa, T., Neurogastroenterol Motil, 22, 4, 446, 452, 20100400
Role of nitrergic nerves in the regulation of motility of the omasum and abomasum in healthy sheep (Ovis aries)., Onaga T, Hara N, Shimizu Y, Veterinary research communications, 33, 1, 33, 48, 20090100, Refereed
Localization of CCK-1R in the omasum and role of CCK in the regulation of omasal contractions in sheep., Onaga T, Sugita A, Wakaiki R, Hara I, Kagawa K, Kirisawa R, Hayashi H, Domestic animal endocrinology, 35, 2, 231, 244, 20080800, Refereed
Localization and secretion of epidermal growth factor in the parotid gland and its intragastric kinetics in sheep., Onaga T, Shimizu Y, Hayashi H, Tsuji M, Endoh D, Okada H, Life sciences, 79, 17, 1616, 1629, 20060900, Refereed
Effect of nitric oxide donor and nitric oxide synthase inhibitor on ruminal contractions in conscious sheep, Onaga, T. Okada, H. Hagiwara, S. Nagashima, C. Inoue, H. Korczynski, W. Kato, S., Research in Veterinary Science, 71, 3, 189, 195, 20010000, Refereed
Effect of nitric oxide synthase inhibitors on the temporal coordination of duodenal contractions and pancreatic exocrine secretion in sheep, Onaga, T. Nagashima, C. Sakata, T., Journal of Comparative Physiology B, 170, 469, 479, 20000000, Refereed
Regional distribution and plasma concentration of peptide YY in sheep , Onaga, T. Yoshida, M. Inoue, H. Yokota, H., PEPTIDES, 21, 5, 655, 667, 20000000, Refereed
Small intestinal UDP-glucuronosyltransferase sheUGT1A07 : Partial purfication and cDNA cloning from sheep small intestine, Kobayashi, T. Tatano, A. Yokota, H. Onaga, T. Watanabe, T. Yuasa, A., Archives of Biochemistry and Biophysics, 364, 2, 143, 152, 19990000, Refereed
Pituitary adenylate cyclase-activating polypeptide (PACAP) induces duodenal phasic contractions via the vagal cholinergic nerves in sheep, Onaga, T. Harada, Y. Okamoto, K., Regulatory Peptides, 77, 1-3, 69, 76, 19980000, Refereed
Effect of L364718 on interdigestive pancreatic exocrine secretion and gastroduodenal motility in sheep, Onaga, T. Mineo, H. Kato, S., Regulatory Peptides, 68, 2, 139, 146, 19970000, Refereed
Effect of oxytocin, arginine-vasopressin and lysine-vasopressin on insulin and glucagon secretion in sheep, Mineo, H. Ito, M. Muto, H. Kamita, H. Hyun, H. S. Onaga, T. Yanaihara, N., Research in Veterinary Science, 62, 2, 105, 110, 19970000, Refereed
Responses of glucose absorption and fructose absorption to prostaglandin E2 in intestinal loops of sheep, Hyun, H. S. Onaga, T. Mineo, H. Kato, S., Research in Veterinary Science, 62, 2, 153, 157, 19970000, Refereed
Effect of C-terminal fragments of cholecystokinin on plasma insulin and glucagon concentration in sheep, Mineo, H. Kamita, H. Muto, H. Ito, M. Hyun, H. S. Onaga, T. Yanaihara, N., Research in Veterinary Science, 62, 2, 171, 174, 19970000, Refereed
Role of peptide YY in regulation of duodenal motility during the interdigestive period in sheep, Onaga, T. Kubagawa, S. Lee, S. Mineo, H. Kato, S. Naruse, S. Ozaki, T., Journal of Comparative Physiology B, 167, 5, 352, 360, 19970000, Refereed
PACAP stimulates pancreatic exocrine secretion via the vagal cholinergic nerves in sheep, Onaga, T. Okamoto, K. Harada, Y. Mineo, H. Kato, S., Regulatory Peptides, 72, 2-3, 147, 153, 19970000, Refereed
Loperamide does not affect the prostaglandin E2(PGE2)-induced antiabsorptive effect on glucose in the small intestinal loop of sheep, Hyun, H. S., T. Onaga, H. Mineo, and S. Kato., Journal of Animal Physiology a. Animal Nutrition, 76, 80, 89, 19960000, Refereed
Effect of cholera toxin on glucose absorption and net movement of water and electrolytes in the intestinal loop of sheep, Hyun, H. S. Onaga, T. Mineo, H. Kim, J. T. Kato, S., Journal of Veterinary Medicine A, 43, 611, 618, 19960000, Refereed
Comparison of the effects of secretagogues on the net movement of electrolyte and glucose absorption in the proximal and middle small intestine of sheep, Hyun, H. S., T. Onaga, H. Mineo, and S. Kato., Journal of Animal Physiology a. animal Nutrition, 76, 160, 169, 19960000, Refereed
Effect of pituitary adenylate cyclase-activating polypeptide on excrine and endocrine sectetion in ovine pancreas, Onaga, T. Uchida, M. Kimura, M. Miyazaki, M. Mineo, H. Kato, S. Zabielski, R., Comparative Biochemistry and Physiology C, 115, 3, 185, 193, 19960000, Refereed
Effect of benzoic acid and its analogues on insulin and glucagon secretion in sheep, Mineo, H. Ohdate, T. Fukumura, K. Katayama, T. Onaga, T. Kato, S. Yanaihara, N., Europian Journal of Pharmacology, 280, 2, 149, 154, 19950000, Refereed
Effects of vasoactive intestinal polypeptide(VIP) on the net movement of electrolytes and water and glucose absorption in the jejunal loop of sheep, Hyun, H. S. Onaga, T. Mineo, H. Kato, S., The Journal of Veterinary Medical Science, 57, 5, 865, 869, 19950000, Refereed
Effect of postoperative periods on glucose absorption and electrolyte secretion in the intestinal loop of sheep, Hyun, H. S. Onaga, T. Mineo, H. Kato, S., Journal of veterinary Medicine A, 42, 9, 601, 610, 19950000, Refereed
The effect of PGE2 on glucose absorption and net movement of water and electrolytes in the jejunal loop in sheep, Hyun, H. S., T. Onaga, H. Mineo, and S. Kato., Journal of Animal Physidogy a. Anim. Nutr., 74, 185, 193, 19950000, Refereed
Effect of neural blockades, gastrointestinal regulatory peptides, and diversion of gastroduodenal contents on periodic pancreatic secretion in the preruminant calf, Zabielski, R. Kiela, P. Onaga, T. Mineo, H. Gregory, P. C. Kato, S., Canadian Journal of Physiology and Pharmacology, 73, 11, 1616, 1624, 19950000, Refereed
Role of endogenous CCK in regulation of interdigestive pancreatic exocrine secretion in sheep, Tachibana, S. Onaga, T. Mineo, H. Kato, S., Comparative Biochemistry and Physiology, 112A, 1, 103, 109, 19950000, Refereed
Cholecystokinin does not act on the efferent pathway of cholinergic and adrenergic nerves to inhibit ruminal contractions in sheep, Onaga, T. Onodera, T. Mineo, H. Kato, S., Comparative Biochemistry and Physiology, 111A, 1, 51, 58, 19950000, Refereed
Effect of intravenous infusions of cholecystokinin-8 and pentagastrin on plasma concentration of insulin and glucagon in sheep, Mineo, H. Iwaki, N. Onaga, T. Kato, S., Research in Veterinary Science, 56, 3, 298, 302, 19950000, Refereed
Chemical specificity of short-chain tatty acids in stimulating insulin and glucagon secretion in sheep, Mineo, H. Hashizume, Y. Hanaki, Y. Murata, K. Maeda, H. Onaga, T. Kato, S. Yanaihara, N., American Journal of Physiology, 267, 2, E234, E241, 19940000, Refereed
Plasma secretin fluctuates in phase with periodic pancreatic secretion and the duodenal migrating myoelectric complex in calves(共著), Zabielski, R. Terui, Y. Onaga, T. Mineo, H. Kato, S., Research in Veterinary Science, 56, 3, 332, 337, 19940000, Refereed
Effect of perfusion rate and glucose concentration or glucose absorption in intestinal Thiry-vella loop in sheep, Hyun, H. S. Onaga, T. Mineo, H. Kato, S.Seiyu KATO, Journal of Veterinary Medical Sciense, 56, 3, 617, 618, 19940000, Refereed
Local versus peripheral blood administration of cholecystokinin-8 and secretin on pancreatic secretion in calves, Zabielski, R. Onaga, T. Mineo, H. Pierzynowski, S. G. Kato, S., Experimental Physiology, 79, 3, 301, 311, 19940000, Refereed
Pituitary adenylate cyclase-activating polypeptide (PACAP) stimulates exocrine pancreas in conscious preruminating calves , Zabielski, R. Onaga, T. Mineo, H. Okine, E. Kato, S., Comparative Biochemistry and Physiology, 109C, 1, 93, 99, 19940000, Refereed
Exocrine pancreatic responses to CCK-8 and VZP infused during NSA and RSA phase of duodenal MMC in calves-Does pancreatic responsiveness to GI peptides fluctuate periodically, Zabielski, R., T. Onaga, H. Mineo, and S. Kato, Biomedical Research, 15, 371, 374, 19940000, Refereed
The inhibition of interdigestive periodic pancreatic secretion by PYY in dogs, Onaga, T., R. Zabielski, S. Kato, S. Naruse, and T. Ozaki, Biomedical Research, 15, 377, 381, 19940000
Periodic fluctuation in pancreatic secretion and duodenal motility investigated in neonatal calves, Zabielski, R. Onaga, T. Mineo, H. Kato, S., Experimental Physiology, 78, 5, 675, 684, 19930000, Refereed
Effect of peripheral and local VIP administration on secretion of exocrine pancreas and on electrical and mechanical activity of duodenum in preruminating calves, Zabielski, R., T. Onaga, H. Mineo, and S. Kato, Biomedical Research, 13, 243, 246, 19920000, Refereed
Effect of intravenous infusion of insulin, glucose and tolbutamide on pancreatic exocrine secretion in sheep, Kato, S., S. Matsumoto, H. Kojima, H. Mineo, T. Onaga, & K. Kikuchi, Japanese Journal of Zootechnology and Sciense, 61, 360, 365, 19900000, Refereed

Research Grants & Projects

Study on peptidergic regulations of gastrointestinal functions
Study on the regulatory mechanism of gastrointestinal motility in ruminants


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