School of Veterinary Medicine, Department of Veterinary Medicine
大杉剛生 オオスギ タケオ
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Last Update :2020/09/01

Researcher Profile and Settings

Name

OHSUGI Takeo

Affiliation (Master)

School of Veterinary Medicine, Department of Veterinary Medicine

Affiliation & Job

Department of Laboratory Animal Sciences, School of Veterinary Medicine
Professor

Education

  1980 04  - 1982 03 , Hokkaido University, School of Veterinary Medicine
 - 1982 , Hokkaido University
  1976 04  - 1980 03 , Rakuno Gakuen University, Faculty of Dairy Science
 - 1980 , Rakuno Gakuen University, Faculty of Veterinary Medicine

Degree

Ph.D.

Academic & Professional Experience

  2014  - Today, Professor, Department of Laboratory Animal Science, School of Veterinary Medicine, Rakuno-Gakuen University
  2001  - 2014 , Associate Professor, Institute of Resource Development and Analysis, Kumamoto University
  1998  - 2000 , Senior Lecturer, School of Medicine, Juntendo University
  1992  - 1997 , Assistant Professor, Department of Virology, School of Medicine, Kurume University
  1988  - 1991 , Research Associate, Medical School, Osaka University
  1986  - 1987 , postdoctoral fellow, Department of Microbiology and Immunology, Lousiana State University medical school in Shreveport

Research Activities

Research Areas

Life sciences, Virology
Life sciences, Molecular biology
Life sciences, Laboratory animal science

Published Papers

High expression of NAMPT in adult T-cell leukemia/lymphoma and anti-tumor activity of a NAMPT inhibitor., Kozako T, Aikawa A, Ohsugi T, Uchida YI, Kato N, Sato K, Ishitsuka K, Yoshimitsu M, Honda SI, European journal of pharmacology, European journal of pharmacology, 865, 172738, 20191200, Refereed
A novel mouse model of adult T‐cell leukemia cell invasion into the spinal cord, Takeo Ohsugi, Shuhei Tanaka, Keigo Iwasaki, Yusuke Nagano, Tomohiro Kozako, Kazuya Matsuda, Takuya Hirose, Kazushige Takehana, Animal Models and Experimental Medicine, Animal Models and Experimental Medicine, 2, 1, 64, 67, 20190100, Refereed
Novel small molecule SIRT2 inhibitors induce cell death in leukemic cell lines., Kozako T, Mellini P, Ohsugi T, Aikawa A, Uchida YI, Honda SI, Suzuki T, BMC cancer, BMC cancer, 18, 1, 791, 20180800, Refereed
Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas, Blood, Blood, 128, 462, 20161200, Refereed
Stevens-Johnson syndrome/toxic epidermal necrolysis-like disease in human T-cell leukemia virus type 1 Tax transgenic mice, Takeo Ohsugi, Current Trends in Immunology, Current Trends in Immunology, 15, 43, 46, 20140100, Refereed
P53 dysfunction precedes the activation of nuclear factor-κB during disease progression in mice expressing tax, a human t-cell leukemia virus type 1 oncoprotein, Takeo Ohsugi, Takaomi Ishida, Tatsuya Shimasaki, Seiji Okada, Kazuo Umezawa, Carcinogenesis, Carcinogenesis, 34, 9, 2129, 2136, 20130900, Refereed
A novel mouse model of adult T-cell leukemia cell invasion into the spinal cord, Ohsugi T, Tanaka S, Iwasaki K, Nagano Y, Kozako T, Matsuda K, Hirose T, Takehana K, Animal Model Exp Me, Animal Model Exp Me, 2, 1, 67, 69, 20090100, Refereed

Books etc

Encyclopedia of Virology Research, Ohsugi,T, Koito, A, Contributor, Human T-cell Leukemia Virus Type 1 (HTLV-1) and Antiviral Enzyme APOBEC3, NOVA Scientific publishers,   2012
JSPS RONPAKU (Dissertation Ph.D.) program abstracts of dissertation for FY 2009, OHSUGI Takeo, Contributor, Molecular analysis of estrogen dependent breast cancer in animal model and cell lines.,   2011

Conference Activities & Talks

Development and molecular analysis of synthetic lethality by targeting EZH1/2 in ATL and HTLV-1-infected cells, Yamagishi, M, Hori, M, Fujiwara, D, Honma, D, Adachi, N, Ohsugi, T, Nakano, K, Nakashima, M, Kobayashi, S, Iwanaga, M, Utsunomiya, A, Tanaka, Y, Okada, S, Tsukasaki, K, Toninai, K, Araki, K, Watanabe, T, Uchimaru, K, 18th International Conference on Human Retrovirology HTLV and Related Viruses,   2017 03 07
Tamoxifen inhibits the infiltration of human T-cell leukemia virus type 1-infected cells into organs in a mouse model of adult T-cell leukemia., Tanaka, Y, Kozuka, T, Yamagishi, M, Hirose, T, Nagano, Y, Nishii, R, Kitamura, H, Takehana, K, Watanabe, T, Ohsugi, T, 18th International Conference on Human Retrovirology HTLV and Related Viruses,   2017 03 07
Development and Molecular Analysis of Synthetic Lethality By Targeting EZH1 and EZH2 in Non-Hodgkin Lymphomas, Makoto Yamagishi, Makoto Hori, Dai Fujikawa, Daisuke Honma, Nobuaki Adachi, Takeo Ohsugi, Kazumi Nakano, Makoto Nakashima, Seiichiro Kobayashi, Masako Iwanaga, Atae Utsunomiya, Seiji Okada, Kunihiro Tsukasaki, Kensei Tobinai, Kazushi Araki, Toshiki Watanabe, Kaoru Uchimaru, ASH 58th annual meeting & exposition,   2016 12 04


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